“Buy or Bye”™ – Daily Fantasy Football Plays for Week 10 2025 Cash Games

By Ha Kung Wong 

Twitter: @FBGarbageTime

In 2024, we were over 70% for cash lineups again and we’re back with more Daily Fantasy Football advice for Cash Games for Week 10 of the 2025 season!

You’re welcome.

As usual, before we get to winning you more bragging rights (and DFS cash), remember, the point of this article is not just to give you one or two lineups for each site, it’s to give you examples of a few POSSIBLE lineups.  Getting exposure to a few different lineups is always a good idea, so don’t forget to mix and match additional lineups from my suggestions below.  Trust me, it’s a lot more fun that way AND you’ll improve your chances of cashing!

Let’s get to winning you some CASH in Week 10 of the 2025 NFL season!

Daily Fantasy Football

Cash Games, for those who don’t know, are essentially the lowest risk games.  They include “50/50” games, in which half the entrants win about 1.8x the entry fee, and “Double Ups”, in which slightly less than half the entrants win 2x the entry fee.

Since there’s so many different sites, and I can’t cover them all, I’ve decided to cover just the most popular sites, including Fan Duel, Draft Kings and Yahoo! Daily Fantasy.

First of all, as a general rule for 50/50 Cash Games, there’s a basic target of points per salary cap spent that you’d like to look for:

  • For Fan Duel try to target at least 2 fantasy points per $1000 spent.
  • For Draft Kings, try to target at least 2.5 fantasy points per $1000 spent.
  • For Yahoo! Daily Fantasy, try to target at least 0.6-0.7 fantasy points per $1 spent.

Remember, this article is not focused on GPP (Tournament) Games, JUST Cash Games.  Feel free to use a few of these suggested players as a base when constructing a GPP lineup, but you’ll have to take some chances on a few low cost, upside players as well.

As per usual, I’m going to provide you with a few sample lineups on each site and give you a few notes to consider.  You’re welcome.

So, without further to do, here are my suggestions for the Best Daily Fantasy Football Plays for Cash Games and player props for Week 10 contests.

FanDuel 

Draft Kings 

Yahoo! DFS

Game Notes:

  • For those new to this column, note that I never advocate against you paying up at any particular position for DFS.  We all know that the likes of Josh Allen and Jahmyr Gibbs are probably going to have the most consistent upside in terms of potential fantasy points from week to week.  But remember that DFS is a salary cap game.  You can feel free to sprinkle high priced players into your lineups, but you can’t pay up at every position because there’s simply not enough salary to go around.  I try my best each week to provide my thoughts on how you might want to balance your cash lineups in terms of points potential and salary.
  • My approach to DFS in Week 10 is to anchor my lineup with a stud QB or WR and fill in value elsewhere.
  • No “Free Square of the Week”™ this week, but still plenty of value.
  • The Los Angeles Rams @ San Francisco 49ers game has the second highest over/under of the main slate (49.5), so there’s plenty of potential here.  For the Rams, I like Kyren Williams and Puka Nacua.  The 49ers defense is solid, but they have just the 26th ranked rush defense, so Williams should find some room to run, particularly coming off a 114-yards and 1 TD performance against the similarly bad 28th ranked Saints defense.  Nacua has a tougher road against a better pass defense, but even in limited games due to injury, has the most receptions (8.71) and 2nd most yards (101) per game this season among WRs, so he’s mostly matchup proof with a high floor.  For the 49ers, I’m in on George Kittle, Jauan Jennings and Christian McCaffrey in that order, mostly due to value.  Jennings is cheap and now averaging over 6 targets per game over his last 3, while Kittle has averaged 4 receptions per game since coming back from injury and is always a threat to score.  CMC is CMC and should be the focal point for the 49ers offense but comes with a pretty hefty price tag.
  • The Baltimore Ravens @ the Minnesota Vikings has the 3rd highest over/under of the week (48.5), but I like the Ravens more.  For the Ravens, I like Lamar Jackson, Zay Flowers and Derek Henry, in that order.  The Vikings haven’t lived up to their defensive reputation being only 25th against the pass and 23rd against the run, meaning every Raven has a shot to score.  Jackson in particular is coming off a 4-TD game in his first game back from injury and now has the most passing TDs per game (2.8) in the NFL.  The Ravens defense is now essentially 100% healthy, so I’m not as keep on the Vikings, but sprinkling in a little Justin Jefferson doesn’t help if you have the cap space.
  • It’s not for the faint of heart, but Jacoby Brissett is near minimum, if not absolute minimum, price across industry.  In 3 starts this season, Brissett is averaging 286 passing yards and 2 passing TDs.  Add in a rushing TD in Week 9 and that’s some serious upside for essentially nothing.  Yes, the Seahawks defense is legit, which is why you’ll probably have to hold your breath a little during the game, but sometimes the risk is worth the price.  I also like playing Trey McBride if you have the cap space, and Emari Demarcado if you have to punt your flex.  The likely negative game script should give all three plenty of opportunity to meet their numbers if only in garbage time.
    Jacoby Brissett 2025 Game Log
    Pass Pass Pass Pass Pass Pass Pass Rush Rush Rush
    Date Opp Result Cmp Att Cmp% Yds TD Int Rate Att Yds TD
    2025-11-03 DAL W, 27-17 21 31 67.7 261 2 0 115.1 5 4 1
    2025-10-19 GNB L, 23-27 25 36 69.4 279 2 0 110.8 6 26 0
    2025-10-12 IND L, 27-31 27 44 61.4 320 2 1 89.2 3 19 0
  • Jaxon Smith-Njigba leads all WRs in receiving yards per game (118), target share (38.2%) and yards per route run (4.56), plus he has the 4th most receptions per game of any WR in the NFL.  Sometimes I don’t need to sell the player, but he comes with a hefty price tag.  If I go cheap at QB, I’m trying to jam him in, especially against the 20th ranked Cardinals pass defense.
  • Emeka Egbuka is coming off a bye and should be back to 100% and ready to also get back to his team-leading target share (24.0%) and yards per route run (2.26). The Patriots defense is legit, but Egbuka should be targeted often by Baker Mayfield.
  • TreVeyon Henderson gets the back field to himself again in Week 10 after Rhamondre Stevenson is ruled out again and gets to face the 24th ranked Buccaneers run defense. Henderson had 87 yards on 18 touches last week in a similar situation, is still super cheap and gets another smash opportunity, so lock him in.
  • Wan’Dale Robinson is Jaxson Dart‘s favorite target and is coming off a whopping 11 targets in Week 9.  He’s averaging 7.56 targets this season and I’d take that against a Bears defense that has struggled against the pass.
  • With Travis Hunter on IR and Brian Thomas Jr. ruled out, Parker Washington should lead the Jaguars in targets, even with newly acquire Jakobi Meyers in town.  Washington has had at least 9 targets 3 times this season, including each of the past 2 games. He’s very cheap and makes for a great cap saver with upside.
  • On defense, I love taking value and paying down, so I’m in on both the Jacksonville Jaguars Defense against the Davis Mills-led Texans and Baltimore Ravens Defense now that their healthy against the struggling Vikings.

Good luck everyone with your Week 10 Cash Lineups, and I’ll see you next week for some Week 11 Cash Lineup suggestions!